Octopuses and squid are masters of RNA editing while leaving DNA intact

Citations

S. Alon, et al. The vast majority of transcripts within the squid nervous system are extensively recoded by A-to-I RNA modifying. eLife. January 8, 2015. doi: 10.7554/eLife.05198. 

N. Liscovitch-Brauer, et al. Commerce-off between transcriptome plasticity and genome evolution in cephalopods. Cell. Vol. 169, April 6, 2017, p. 191. doi: 10.1016/j.cell.2017.03.025.

D. Jiang and J. Zhang. The preponderance of nonsynonymous A-to-I RNA modifying in coleoids is nonadaptive. Nature Communications. Vol. 10, November 27, 2019. doi: 10.1038/s41467-019-13275-2.

M. Moldovan, et al. Adaptive evolution at mRNA modifying websites in soft-bodied cephalopods. PeerJ. Vol. 8, November 27, 2020. doi: 10.7717/peerj.10456. 

Y. Shoshan, et al. Adaptive proteome diversification by nonsynonymous A-to-I RNA modifying in coleoid cephalopods. Molecular Biology and Evolution. Vol. 38, September 2021, p. 3775. doi: 10.1093/molbev/msab154.

O. Gabay, et al. Panorama of adenosine-to-inosine RNA recoding throughout human tissues. Nature Communications. Vol. 13, March 4, 2022. doi: 10.1038/s41467-022-28841-4. 

C. B. Albertin, et al. Genome and transcriptome mechanisms driving cephalopod evolution. Nature Communications. Vol. 13, Might 4, 2022. doi: 10.1038/s41467-022-29748-w. 

Ok.J. Rangan and S.L. Reck-Peterson. RNA recoding in cephalopods tailors microtubule motor protein operate. bioRxiv.org. September 25, 2022. doi: 10.1101/2022.09.25.509396.

J. J. C. Rosenthal and E. Eisenberg. In depth recoding of the neural proteome in cephalopods by RNA modifying. Annual Evaluate of Animal Biosciences. Vol. 11, 2023, p. 11. doi:  10.1146/annurev-animal-060322-114534.