Anti-ageing drugs could make more organs viable for transplants

Anti-ageing drugs could make more organs viable for transplants


Surgeons finishing up a kidney transplant

Christopher Furlong/Getty Pictures

Medicine that clear away worn-out cells could enhance the success of transplanted organs from older donors, based on analysis in mice.

As we grow old, some cells cease dividing, however linger as an alternative of dying off. These so-called senescent cells accumulate in our organs, releasing chemical compounds that may set off irritation and promote illness.

When an organ from an older donor is transplanted right into a youthful individual, senescent cells within the transplanted organ can activate senescence within the recipient’s personal cells. This “switch” of ageing can worsen …